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Can HIV Drugs Prevent HIV?

Research on Pre-Exposure Prophylaxis (PrEP)



Pre-exposure prophylaxis, or PrEP, is an experimental strategy in which HIV-uninfected people take antiretroviral medication (singly or in combination) once-daily to protect themselves against HIV infection. PrEP has not yet been proven to have any efficacy or to be completely safe. It is, however, one of several experimental prevention interventions (including microbicides and vaccines) which could potentially provide additional modes of minimizing the risk of HIV infection.


In February 2005, AIDS advocacy groups issued a sign-on statement in support of pre-exposure prophylaxis (PrEP) research. The sign-on statement prompted a comprehensive and welcome response from the investigators of ongoing trials studying PrEP in men who have sex with men.


The dialogue between advocates and scientists is an important step. But there is a need for continued, informed community advocacy around PrEP research in the United States and around the world.


We therefore reiterate that we must swiftly and effectively answer the question: Does PrEP work and is it safe? To achieve this goal, trial sponsors, manufacturer of both drugs currently being tested for use in PrEP (Gilead), clinicians and community groups must work together to address several outstanding issues.

FULL POSITION STATEMENT AND BACKGROUND INFORMATION AVAILABLE BELOW.

Additional Materials Available at: www.prepwatch.org



Sign-On Statement on PrEP Research

Issued by CHAMP, AIDS Vaccine Advocacy Coalition (AVAC), Global Campaign for Microbicides, and Treatment Action Group (TAG) with request for endorsement, April 2006

COMMUNITY FORUM MATERIALS: SPEAKER PRESENTATIONS

Edd Lee, AVAC: Overview PowerPoint Presentation


Richard Jefferys, TAG: Research Thus Far
PowerPoint Presentation


Albert Liu, PrEP Researcher, San Francisco
PowerPoint Presentation


Pedro Goicochea, PrEP Researcher, Peru PowerPoint Presentation


Raffi Babakhanian, CHAMP: Prevention Activist Perspectives PowerPoint Presentation


Edd Lee, Moving Forward PowerPoint Presentation

COMMUNITY FORUM MATERIALS: OUTREACH VIDEO

Video from Peru used for clinical trial outreach TE QUEREMOS